Gene editing
29 May 2021

A non-viral and selection-free COL7A1 HDR approach with improved safety profile for dystrophic epidermolysis bullosa

 Mol Ther Nucleic Acids. 2021 May 29;25:237-250. doi: 10.1016/j.omtn.2021.05.015. PMID: 34458008; PMCID: PMC8368800. A non-viral and selection-free COL7A1 HDR approach with improved safety profile for dystrophic epidermolysis bullosa […]
11 April 2023

A Review of CRISPR-Based Advances in Dermatological Diseases

Mol Diagn Ther. 2023 Jul;27(4):445-456. doi: 10.1007/s40291-023-00642-5. Epub 2023 Apr 11. PMID: 37041404. A Review of CRISPR-Based Advances in Dermatological Diseases Authors: Lu X, Jin H. […]
20 June 2023

Gene editing with ‘pencil’ rather than ‘scissors’ in human pluripotent stem cells

Keywords: Human pluripotent stem cells, Disease modeling, Ex vivo therapy, Isogenic pair, Base editors, Prime editor, Base substitution, Cas9
11 October 2023

CRISPR/Cas9 Based Non-viral Gene Editing Therapy for Topical Treatment of Recessive Dystrophic Epidermolysis Bullosa

Molecular Therapy: Methods & Clinical Development – JOURNAL PRE-PROOF CRISPR/Cas9 Based Non-viral Gene Editing Therapy for Topical Treatment of Recessive Dystrophic Epidermolysis Bullosa Authors: Xianqing Wang 1, Xi […]
20 January 2024

CRISPR technology: A decade of genome editing is only the beginning

Science. 2023 Jan 20;379(6629):eadd8643. doi: 10.1126/science.add8643. Epub 2023 Jan 20. PMID: 36656942. CRISPR technology: A decade of genome editing is only the beginning Authors: Joy Y […]
24 March 2024

Challenges and progress related to gene editing in rare skin diseases

Adv Drug Deliv Rev. 2024 Mar 23:115294. doi: 10.1016/j.addr.2024.115294. Epub ahead of print. PMID: 38527624. Challenges and progress related to gene editing in rare skin diseases […]